IS EXPLORATION OF ALTERNATE IMMUNE PATHWAYS NEEDED IN HIDRADENITIS SUPPURATIVA? A CASE OF ATOPIC DERMATITIS AND CONCURRENT HIDRADENITIS SUPPURATIVA RESPONDING TO DUPILUMAB

Hidradenitis suppurativa (HS) is an inflammatory dermatosis associated with overactive T helper 1/T helper 17 (Th1/Th17) cells.HS has been effectively treated with biologic medications; however, many such biologics lack large randomized controlled trials.Only one such biologic, adalimumab, has been approved by the US Food and Drug Administration (F

MicroRNAs in small extracellular vesicle (sEV-miRNAs) have been widely investigated as crucial regulated molecules secreted by tumor cells to communicate with surroundings.It is of Counter-Top Product great significance to explore the loading mechanism of sEV-miRNAs by tumor cells.Here, we comprehensively illustrated a reasoned loading pathway of b

This paper presents some results obtained by the investigation of the discursive construction of the intolerant identity, developed within the Laboratory of Studies on Intolerance.The theoretical framework is that of French Pushbutton Defrost Fridge Thermostat discursive semiotics.The objective of the paper is to show how intolerant (racist, fascis